EGF: Epidermal Growth Factor (EGF). Promotes dermal repair by increasing its rate of self-regeneration. Produces an increase in the proliferation of keratinocytes in the corneal epithelium, endothelial cells, and fibroblasts (increases protein and glycosaminoglycan synthesis). It has high powers of biostimulation and tissue regeneration. Its application reduces wound healing time. It intervenes in processes involved in wound healing phases such as division, differentiation, protein expression, enzyme production, cellular angiogenesis, and the degradation and production of the extracellular matrix.

HYALURONIC ACID: Moisturizer (forms a viscoelastic layer thanks to its high water retention capacity). Restructures the biological matrix of the skin.

Among the mechanisms of HA action in healing, its interaction with fibrinogen accelerates the process of thrombin-induced fibrin clot formation. HA binds to the fibronectin molecule and stimulates epithelial migration, in which cellular receptors CD-44 are involved, migrating to the same region. These are the major receptors for HA, specifically binding to it. It activates reepithelization, regulates the proliferation and migration of keratinocytes and fibroblasts, thus reducing the roughness of the newly formed epidermis. The repaired tissues are of better quality, and the scars are less significant. In vivo, HA of medium molecular weight used in wounds interacts with the CD44 receptor, stimulates the immune system, and activates healing processes.
TEA TREE OIL: Contains a combination of terpenes, hydrocarbons, monoterpenes, sesquiterpenes, and their associated alcohols, giving it a potent antimicrobial activity, especially useful for treating acne vulgaris.

GRAPESEED OIL: Very rich in antioxidants and has a high content of oleic and linoleic essential fatty acids. It has anti-inflammatory, antimicrobial, and wound-healing effects. Contains resveratrol, which has antimicrobial activity, inhibiting the growth of bacteria such as Staphylococcus aureus. Produces catechins that inhibit the lipase produced by P. acnes, which is key in the pathogenesis of acne as it is responsible for the hydrolysis of sebum and the release of inflammatory compounds. It also contains a significant amount of phytosterols, phospholipids, and vitamin E, which are responsible for its antioxidant activity, giving it a great regenerating and protective power for the skin. It provides regeneration, prevents skin dehydration, and smooths the skin.

ALOE VERA: Promotes wound healing and skin lesion repair, prevents fungal infections, and has anti-inflammatory and anti-tumor properties. It also enhances the  cutaneous absorption of other active ingredients. It has antimicrobial activity against gram-positive bacteria such as Staphylococcus aureus and Staphylococcus epidermidis, which are involved in acne.

CALENDULA: A plant with antibacterial and

anti-inflammatory properties. It inhibits the growth of several bacteria and fungi, including Staphylococcus aureus, P. acnes, and S. epidermidis. It is also emollient, reepithelizing, scar-healing, and antioxidant. It reduces inflammation and leukocyte infiltration. It has significant beneficial effects on atopic dermatitis and sensitive skin.

VITAMINS: Vitamin E acts against free radicals by inhibiting hydrogen peroxide. Vitamin A, or retinol, acts on skin flexibility and density by controlling the keratinization and healing processes. It is a powerful antioxidant that prevents premature aging and stimulates collagen production, which is responsible for the structural formation of skin layers, contributing to smoother, even, and more radiant skin, with a younger appearance. It also stabilizes melanocytes, reducing the appearance of spots, increases epidermal turnover, and acts as a sebum regulator in oily skin. Panthenol is the precursor of vitamin B5, which acts in many metabolic processes, accelerating tissue regeneration and improving skin hydration. Even very dry skin regains its integrity and flexibility.

ZINC: Acts as an inhibitor of the 5-alpha-reductase enzyme, slowing down hyperseborrhea. It also has anti-inflammatory and wound-healing actions. It acts as a dual antioxidant by helping maintain superoxide dismutase enzyme activity and increasing metallothionein concentrations, which destroy free radicals. Zinc is also known for its antiseptic activity, as it inhibits the proliferation of bacteria and fungi. Studies have been conducted on microorganism cultures such as E. Coli, S. Aureus, or C. Albicans.